REGISTRATION REQUEST and ABSTRACT SUBMISSION DEADLINE: May 21, 2024

To attend the conferences Jacques Monod, an abstract submission is mandatory,

Registrations request without abstract submission will not be processed, except in specific

cases (i. g. for Publishers : please contact chairperson).

Chairperson: Gaëlle Legube

Centre de Biologie Integrative (CBI), 118 route de Narbonne, 31062, Toulouse, France

Phone : +33 (0)5 61 55 88 94

Email : gaelle.legube@univ-tlse3.fr

Vice-chairperson: Houra Merrikh

Department of Biochemistry, Vanderbilt University, Nashville, TN, 37027, USA

Phone : +1 615 343 3846

Email : houra.merrikh@vanderbilt.edu

To maintain genome integrity, cells have developed a complex signaling network, known as the DNA damage response or DDR, that regulates DNA replication, DNA repair and cell cycle checkpoints. Failure to properly respond to DNA damage leads to genomic instability which is an underlining cause of various human genetics syndromes and associated with many age-related diseases, such as cancer or neurodegeneration.

Over the recent years, it has become evident that RNAs and transcription are major players in the maintenance of genome stability. Not only, they are considered as main threats that challenge DNA integrity, by interfering with DNA replication but are they also now recognized as an integral component of the mechanisms that repair DNA damage arising on the genome. 

The program of the proposed meeting is designed to cover these topics, from the mechanisms that trigger instability on transcribing genomic loci including through the formation of R-loops, to the direct role of RNAs and transcription in repair mechanisms and in disease onset.

The meeting will cover the following topics:

               1. RNA:DNA hybrids: the good and the bad

               2. Transcription-replication conflict as a source of genome instability

               3. Transcription-induced genetic instability and RNA in diseases

               4. RNAs and transcription in DNA damage repair

               5. RNAs and transcription in chromatin, chromosome dynamics and nuclear compartmentalization

               6. RNAs and Telomere maintenance

Registration fee (including board and lodging)

510 € for PhD students
740 € for other participants

Application for registration   details here :
The total number of participants is limited to 115 and all participants are expected to attend for the whole duration of the conference. Selection is made on the basis of the affinity of potential participants with the topics of the conference. Scientists and PhD Students interested in the meeting should deposit on line :

- their curriculum vitae
- the proof of their student status
- the list of their main publications for the 3 last years
- the abstract of their presentation:

The abstract must respect the following template: TemplateResumeFile
- First line: title
- Second line: list of authors. Presenting author underlined
- Third line: author's addresses
- Fourth line: e-mail of the presenting author
Abstracts should be no longer than an A4 page and preferably be submitted in Times New Roman, font size 10 pts. No figures. ".docx" file format.

After deadline, the organizers will select the participants. Except in some particular cases approved by the Chairperson, it is recommended that all selected participants present their work during the conference, either in poster form or by a brief in- session talk. The organizers choose the form in which the presentations are made. No payment will be sent with application. Information on how and when to pay will be mailed in due time to those selected.